Auto Update - Access to the path 'XXXXXXXXXXXX' is denied.
One common path is: Access to the path 'BOSecMRUList' is denied.
The operating system / network security is attempting to update a security protected Epicor file.
In this circumstance, right click on the Epicor icon, click "Run As Administrator", and the update should complete successfully.
This action may require a network administrator to authenticate to approve the update.